Devex Newswire reports that the country received 1.7 million doses of the Oxford-AstraZeneca COVID-19 vaccine from the global distribution facility in early March. The government paused its vaccine rollout after several European countries suspended their use of the vaccine due to concerns about blood clots. The country has only distributed 1,000 doses since launching the vaccination campaign on April 19.

Studies by the Africa Centres for Disease Control and Prevention found that Vaccine hesitancy is a big obstacle. In study only 59% of respondents in DRC were willing to be vaccinated against COVID-19. Overall, respondents were wary of the safety of COVID-19 vaccines. The exception is Ethiopia, where 94% of respondents were willing to be vaccinated.

Dr. John Nkengasong, Africa Centre For Disease Control (CDC) director is urging African countries to accept the vaccine that is available to them. “We do not have choices,” he said at a briefing on Thursday. WHO’s Africa director, Dr. Matshidiso Moeti, applauded DRC’s “extremely wise” and “very generous” decision to return the vaccines for use elsewhere.

The World Bank previously found that out of 128 countries it surveyed, only 30% had plans for scaling up the necessary workforce to deliver vaccines.

The post DR CONGO RETURNS ITS COVID VACCINES first appeared on CPAN WORLD.

If there are limited vaccine supplies Government Health ministries can increase the gap between the two doses of Covid-19 Vaccines to 6 weeks. This is the most recent guidline from the World Health Organisation (WHO). Recall that the Vaccines from Moderna and Pfizer-BioNTech require a booster dose 3 to 4 weeks after the first dose. But with limited vaccine supplies and a projected slower than expected rate of vaccines production the WHO has considered that countries may need more time to get supplies for the second dose even as ather individuals may still be on the process of being administered the first dose. All vaccination can not occur at the same time or within a short period. There will be cues.

The Advisory Committee on Immunization Practices (ACIP) of the United States Center For Disease Control (CDC) has also issued a similar advisory this month on both Pfizer-BioNTech and Moderna mRNA vaccines. The ACIP also added that though the two mRNA Covid-19 vaccines are Bioequivalent they are not interchangeable. The ACIP also advised against co-adminsitration of the mRNA vaccines with other vaccines due to lack of data.

Several countries facing limited vaccine supplies have informed that they will delay administering the booster shot so that more people can benefit from receiving the first dose. With vaccine supplies still limited, the WHO has called for health workers and the most vulnerable groups to be prioritised.

The Strategic Advisory Group of Experts on Immunisation(SAGE) of the WHO beleives intervals of 21 days for the Pfizer-BioNTech vaccine and 28 days for Moderna are best upheld for maximum efficacy and safety. But after putting prevailing circumstances into consideration SAGE has also advised that in “exceptional circumstances” Health workers may stretch the interval between doses up to 42 days for both the Pfizer-BioNTech vaccine and the Moderna vaccine. SAGE also recommended that the two vaccines should only be administered in settings that can deal with a potential anaphylactic reaction.

The WHO SAGE also advised that in situations where there was a shortage of vaccines, people who had been infected with COVID-19 in the previous six months and therefore likely had immunity could opt to postpone vaccination, but stressed that it was not a recommendation to exclude individuals on that basis.

The spokesperson for the WHO SAGE, Alejandro Cravioto, however, warned in a virtual press briefing that the evidence does not go beyond the six-week cut off.

According to the experts both vaccines are very similar, though storage requirements for the Pfizer vaccine is at -70 degrees Celsius while Moderna doses can be stored at -20 C.

Don't forget to drop a comment in the comments section.

The post BREAKIING : WHO OKAYS 6 WEEK DELAY FOR COVID-19 BOOSTER SHOT first appeared on CPAN WORLD.

Astra Zeneca owners of the worlds largest Corona Virus Vaccine production facility located in india have confirmed that 5 people have lost their lives in a fire which gutted the place late last week.

Indian government officials also confirmed the fire which started on thursday in the city of Pune in Maharashtra state. Large smoke clouds were seen erupting from a multi-storey building in India's Serum Institute Indranil's (SII) massive headquarters complex. Government officials were reported to have sent seven fire trucks from the local fire station the site.

The government beleives the fire could have been caused by an electrical fault during construction work. Fire official Prashant Ranpise said what caused the fire was not immediately clear, but it was contained within a facility under construction to boost production capacity of the AstraZeneca coronavirus vaccine.

Serum Institute Indranil's Chief Executive Adar Poonawalla confirming the incident on Twitter wrote, "We have learnt that there has unfortunately been some loss of life at the incident, We are deeply saddened and offer our deepest condolences to the family members of the departed." Pune Mayor confirmed 4 people had been evacuated from the inferno while 5 had lost their lives.

The Indian regulatory Authority had approved two vaccines in January this year-- COVISHIELD produced by the Serum Institute Indranil (on behalf of Astra Zeneca) and COVAXIN produced by local firm Bharat Biotech.

Astra Zeneca is the world largest vaccine maker but the company has said the fire will not affect production of the Corona virus vaccine brand known as COVISHIELD. The company has developed a Corona Virus Vaccine in colaboration with Oxford university and Novavax Inc and licensed production to the Serum Institute Indranil (SII). SII had been contracted to produce a billion does of the vaccine developed by AstraZeneca and Oxford University. The company hopes to increase production capacity from 1.5 billion doses to 2.5 billion doses annually by the end of this year. The new facility gutted by fire is a big part of the exoansion plan.

The company was in the process of producing and stockpiling 50 Million doses a month as from April 2021 to meet growing demand in the world oopulation as the pandemic rages on. They also have plans to increase production to 100Million doses. The AstraZeneca vaccine is already in use in India, Bangladesh, Nepal, the Maldives and Bhutan.

Astra Zeneca officials said production of COVISHIELD will not be interupted because the company had multiple production work centers in different buildings as a production strategy and contingency plan. Though the SII company is estimating delays in launching new products and revenue losses of about $137 Million Dollars. Serum Institute is the world's biggest vaccine manufacturer by volume and has been contracted by the World Health Organization to supply and distribute 200 million doses to COVAX a consortium comprising GAVI, CEPI and WHO for distribution and inoculations to poor countries. Some Wealthy countries have already bought up 75% of the 12 billion coronavirus vaccine doses expected to be produced by companies globally this year. Consequently, Astra Zenenca's SII contract is likely to produce most of the vaccines that will be needed by developing countries.

WHAT DOES THIS MEAN FOR NIGERIA?

Many low- and middle-income countries like Nigeria, Bangladesh, Brazil, are depending on SII delivering the AstraZeneca vaccine. India itself had already began one of the world's biggest vaccine rollouts this in January, aiming to vaccinate 300 million people by July with both COVISHILED and COVAXIN.

With production interuption expected doses in these countries could be delayed. Also since two doses of the vaccine within a space of 3 months are required an interruption of vaccine supply could truncate complete vaccination plans in countries where individuals have already received their first shots.

Lets know what you think. Don't forget to drop a comment

The post FIRE CONSUMES WORLDS LARGEST CORONA VIRUS VACCINE PRODUCTION PLANT: first appeared on CPAN WORLD.

The Minister of State for health Dr. Olorunimbe Mamora and the Chairman Presidential Task Force on Covid 19 Mr Boss Mustapha have both advised that Nigerians do not become complacent once they receive their first dose of the Covid-19 vaccine. They have insisted that safety protocols involving frequent handwashing, use of sanitizers and face masks in public remain in force and will be enforced to the letter.

The government officials have made this assertions in the light of ongoing efforts by the Federal government to acquire the Covid-19 vaccines and initiate distribution nationwide based on a planned strategy. Public health experts have also advised that Vaccines will only facilitate 95% immunity against the prevailing strain of Corona virus and there is still a very small window of opportunity or risk of infection. The government officials have also advised that even though individuals may have been vaccinated and acquired immunity, they could still be carriers and transmit the virus to individuals who are at risk of contracting the disease. Consequently individuals are strongly advised to sustain all safety protocols.

While briefing the Presidential Task Force on Covid-19 earlier this month the Minister for Health Dr Osagie Ehanire reported that there was a reduction in case fatalities. He warned Nigerians not to let down their guard even as case fatality rates were reducing.

The current Corona virus pandemic has claimed millions of lives worldwide in the past 2 years and has necessitated what could eventually become the costliest vaccine development effort and biggest vaccination campaign on history.

Many Clinical trials are ongoing world wide both for drug treatment regimens and Vaccines. Drugs are meant for  treatment of already infected individuals exhibiting symptoms of illness while vaccines are meant to prevent the disease by stimulating immunity in individuals whom have been administered the vaccines.

According to the World Health Organization (WHO) vaccines work by training the body's immune system (natural defense mechanism) to recognize and fight off antigens like Viruses and Bacteria. The vaccines themselves contain microbial part or whole viruses which have been inactivated. The body is able to keep records of these microbes when exposed to them via vaccines thereby developing a natural defense against them. If infected by the virus, the body would have enough antibodies to combat the Virus and prevent full blown disease. WHO currently recognizes more than 50 Covid-19 vaccine candidates undergoing clinical trials. COVAX is the consortium comprising WHO, GAVI and CEPI that is responsible for ensuring adequate vaccine distribution to nations and prioritizing at risk individuals. Currently the vaccines which have been released require administration of a first dose and then a booster dose 3 weeks later to activate the recipient’s immune system and minimize the risk of infection from the virus.

A vaccinated person may not fall sick if infected but can still transmit the virus to friends, family and close contacts.

Lets know what you think in the comments section

The post DO NOT LOWER YOUR GUARD : MINISTER FOR HEALTH first appeared on CPAN WORLD.